Date: 09.04.2012

can you learn in your sleep?

Learning in your sleep.

Apparently we can learn simple responses while we are sleeping. Unfortunately we can’t pick up French from playing the audio recording overnight. From Ed Yong over at The Scientist:

Several groups have tested for advanced forms of learning during sleep, like picking up the links between pairs of words. All such experiments have failed. The only positive results came from studies showing that a very basic form of learning known as classical conditioning can occur in sleeping rats and infants, which begin to associate two stimuli—say, a tone and a puff of air—if they are presented together.

By contrast, Arzi’s experiments used a different technique called “trace conditioning,” where the tone and the smells are separated by more than a second. “This is considered a more advanced type of learning, and unlike classical conditioning, it depends on the hippocampus,” she said. “This is the type of learning associated with more complicated cognitive tasks, and therefore finding it in sleep is potentially important and novel.”

Arzi also took steps to ensure that her subjects were not inadvertently waking up. Throughout her study, a sleep technician monitored the volunteers’ brain activity and halted the experiment whenever they showed signs of rousing. All such trials were left out of the final analysis.

Arzi’s volunteers only learned a very simple response, and it is not clear if we can pick up more complex information while sleeping. “This does not imply that you can place your homework under the pillow and know it in the morning,” she said. “There will be clear limits on what we can learn in sleep, but I speculate that they will be beyond what we have demonstrated.”

one track enzymess

A 3D render of an enzyme

Enzymes that catalyze the most important biological reactions generally have only one function. Other enzymes can carry out multiple less important reactions. From Science News:

Of the 1,081 enzymes studied, 404 were generalists that carried out multiple chemical reactions. The 677 specialist enzymes, it turned out, were essential for the bacterium’s survival, for example tasked with turning genetic instructions into proteins.

Revealing where the generalists and specialists do their stuff in a metabolic network could help scientists identify starter enzymes for designing new drugs, fuels and other chemical products. It also may help biologists create organisms from scratch, says Pablo Carbonell, a synthetic biologist at the University of Évry-Val-d’Essonne in France.

The work clears up a long-standing question about promiscuity and monogamy among enzymes. Enzymes act on what scientists call substrates; for example amylase, an enzyme in saliva, breaks down the substrate starch. For more than 100 years enzymes have been presented as exceedingly loyal to their substrates. But the growing number of promiscuous enzymes that interact with multiple substrates and carry out multiple reactions have forced scientists to face the fact that all enzymes aren’t the dedicated, loyal players they’ve been made out to be.

 

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