sobering up with nanoparticles

Martini

In keeping with today’s theme of alcohol-related science (see today’s earlier post), Popular Science recently had a write-up on using enzymes encapsulated in nanoparticles to help mice sober up after alcohol consumption. From PopSci:

Led by Yunfeng Lu, a chemical and biomolecular engineering professor at UCLA, researchers injected mice with three enzymes related to the breakdown of sugars, and after this worked, they tried it with two enzymes related to the breakdown of alcohol, alcohol oxidase (AOx) and catalase. They wanted to test the enzymes as both an intoxication preventive and a treatment.

When mice were fed a diet of alcohol and the nano-capsule at the same time, their blood alcohol concentrations were greatly reduced within 30-minute increments, compared to mice that were fed just alcohol or alcohol plus one of the enzymes. The team also tested it on drunk mice, and found the treatment greatly lowered yet another enzyme, alanine transaminase, which is a biomarker for liver damage.

For the original research published in Nature Nanotechnology click here.