Year: 2017

splash some water in your whiskey

Scotch, whiskey on the rocks

Whiskey on the rocks.

Add a spalsh of water to your whiskey. If you’ve ever done a whiskey tasting or been to a whiskey bar you’ve probably received this advice. “It’ll bring out the full flavor, especially if it’s a Scotch”. Now there is Science to back that advice up.

Guaiacol

Guaiacol. One of the molecules that give whiskey its characteristic smokiness.

Whiskies have a compound called guaiacol, which gives it its characteristic smokiness. Scotch whiskies typically have more guaiacol than their American or Irish counterparts because it is made with malted barley that has been smoked over a peat fire. Guaiacol is a phenol, and when it is in a solution of ethanol and water, as in whiskey, it tends to interact more with ethanol molecules than water. When whiskey is more concentrated, ethanol and guaiacol form clumps and sink deeper into the glass. But, when its diluted by a splash of water or with an ice cube, the ethanol and guaiacol are more dispersed and accumulate toward the liquid surface. This makes the whiskey smell and taste more flavorful.

So what is the optimal dilution? There is no one answer to this question. The optimal dilution for bringing out a whiskey’s flavor will vary from brand to brand. And giving your whiskey glass a gentle swirl before each sip won’t hurt either.

Read more about the research by Björn Karlsson and Ran Friedman in Scientific Reports.

what is sarin?

What is sarin

Sarin. The deadly gas.

As you’ve probably heard by now, sarin nerve agent was probably behind the death of more than 80 people in Syria last week.  Bashar al-Assad is suspected of using the gas against civilians last week, in what is surely one of the most heinous acts of the ongoing Syrian Civil War. News media showed images of the victims struggling to breathe moving President Donald Trump to engage in a missle strike on Thursday night. The name  sarin is an acronym of the four scientists who created it: Gerhard Schrader, Otto Ambros, Gerhard Ritter, and Hans-Jürgen von der Linde.

But what is sarin, and why is it so deadly?

Sarin is a clear colorless gas, that is  also known as GB. In it’s purest form it has not taste and no odor. The organophosphorus compound is manufactured by humans, and not found in nature. It was first manufactured in the 1930s.

Sarin is deadly becuse it attacks the nervous system preventing proper degradation acetylcholine at neuromuscular junctions. The nerve gas binds to acetylcholinesterase, an enzyme that degrades the acetylcholine, to send signals between nerves and muscles. This means that when someone is exposed to sarin, even at very low levels, their nerve signals don’t communicate properly with muscles. The muscles do not contract or expand as they usually would.  Death after sarin exposure will usually occur as a result suffocation due to the inability to control the muscles involved in breathing. Death usually occurs within 1 to 10 minutes after exposure.

Is there a cure?

There is an antidote for sarin exposure. Atropine treats the physiological symptoms of poisoning, but does not reverse the muscular symptoms. Biperiden is sometimes used as an alternative to atropine due to its better blood–brain barrier penetration and higher efficacy. The drug pralidoxime can regenerate cholinesterase activity, but only if administered within a 5 hour window.

 

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