Category: Genetics (page 2 of 8)

training your cat

An in-depth study of the cat genome reveals details about their history and behaviors.

An in-depth study of the cat genome highlights a variety of genes, including ones for digesting their meaty diets, keen eyesight and good hearing. The researchers found that pet cats also have genes that allow them to respond to positive reinforcement.  From Popular Science:

Cats also seem to have more genes related to digesting fat than other carnivores do, which is important for their super-meaty diets. (Scientists call cats, including wildcats, hypercarnivores.) Cats even have genes that may help them avoid heart disease from their high-fat diets. Polar bear genomes bear similar markers of selection for fat-digesting genes.

To look for the genes influenced by human selection, the researchers analyzed DNA pooled from 23 pet cats, including Cinnamon. They compared the domestic cat DNA with DNA from four wildcats. Among the feline genetic traits that people seem to have chosen are ones that influence how the cat brain responds to rewards. Yep, that means kitty treats! Mice that are missing the mouse versions of some of those genes are poor at learning with food rewards. Perhaps when people first brought cats into their barns and homes, they chose the ones that were more motivated to do things for people in return for tasty tidbits.

The original research appears in PNAS [subscription required].

bigfoot revealed

yeti, sasquatch, bigfoot

Hair samples from the elusive yeti have been analyzed.

Science Magazine brings news of a peer-reviewed analysis of purported Sasquatch hair samples. Genetic analysis reveals that bigfoot is probably not bigfoot.

In 2012, researchers at the University of Oxford in the United Kingdom and the Museum of Zoology in Lausanne, Switzerland, put out a call for hair samples thought to be from anomalous primates. They received 57 hairs from Bigfoot enthusiasts and museums around the world, including samples from Washington, Texas, Oregon, Russia, and India—a few as old as 50 years. Some “hairs” immediately turned out not to be hairs at all, but rather plant or glass fibers; others were too worn to study.

he researchers, led by Oxford geneticist Bryan Sykes, focused on the remaining 37 samples, isolating and cleaning a 2- to 4-centimeter segment of each hair, many of which have been extensively handled by people, contaminating them with foreign DNA. To identify the evolutionary source of each sample, the team determined the sequence of a gene—found inside the mitochondria of cells—that encodes the 12S RNA, which is often used for species identification. Unlike standard DNA, mitochondrial genes are passed only from mother to offspring.

Seven of the samples didn’t yield enough DNA for identification. Of the 30 that were sequenced, all matched the exact 12S RNA sequences for known species, the team reports online today in the Proceedings of the Royal Society B. Ten hairs belonged to various bear species; four were from horses; four were from wolves or dogs; one was a perfect match to a human hair; and the others came from cows, raccoons, deer, and even a porcupine. Two samples, from India and Bhutan, matched polar bear 12S RNA—a surprising finding that Sykes is following up on to determine whether some Himalayan bears are hybrid species with polar bears.

Read the full text of the study free at Proceedings of the Royal Society B.

FDA stops 23andMe

The FDA has asked the genetic testing company 23andMe to stop selling its products. The company manufactures over the counter gene testing kits, that allow a user to discover if they have genes that are linked to certain diseases. The FDA says there is little evidence that these kits work. Read the FDA’s letter to 23andMe here.

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