Tag: cure (page 1 of 2)

child actually not HIV free

HIV medications

A child thought to be cured of HIV is actually still infected. The child received aggressive treatment immediately after birth, which made the virus undetectable. Now the child is showing signs of viral infection again, after two years without therapy. From the Bloomberg:

The child, born to an HIV-infected mother, is now nearly four years old. It was found to have detectable HIV levels in its blood during a routine clinical care visit earlier this month, according to a statement by the National Institute of Allergy and Infectious Diseases.

Doctors had unintentionally stopped giving anti-retroviral treatments to the child at 18 months. When care resumed five months later, medical staff couldn’t detect the virus and the speculation was that the child was free of the illness.

“Obviously, as an individual patient it’s disappointing,” said Anthony Fauci, director of NIAID, in a telephone interview. “But we’re learning very important things. Our capability of detection isn’t good enough. This reservoir is extraordinary, and we need to get better tools to measure it accurately.”

another baby cured of HIV?

Back in March of last year, it was announced that a baby had been cured from HIV, thanks to early and aggressive antiretroviral treatements. Now, we have a second case of it happening.

From Popular Science:

…[A] Los Angeles-born child infected through its mother was treated with the drugs four hours after its birth, last April. Now, with the child approaching its first birthday, the virus appears to have gone into remission.

The HIV medication used in both cases is usually part of a treatment to suppress the virus in infected patients, but the illness, in those other cases, comes back after the patient is taken off the drugs

The patient is still taking medications so they cannot say with any certainty that the drug has cured him. But the virus seems to be operating at depressed levels and the clinicians are optimistic that it is in recession.

adults cured of HIV

HIV Medications

A new report in PLoS Pathogens reports that in 14 adults are have been functionally cured of HIV. This comes after a Mississippi baby was miraculously cured of HIV because of early treatment. Early antiretroviral treatment seems to be important in these cases as well. From a summary in The New Scientist:

Asier Sáez-Cirión of the Pasteur Institute’s unit for regulation of retroviral infections in Paris analysed 70 people with HIV who had been treated with antiretroviral drugs (ARVs) between 35 days and 10 weeks after infection – much sooner than people are normally treated.

All of the participants’ drug regimes had been interrupted for one reason or another. For example, some people had made a personal choice to stop taking the drugs, others had been part of a trial of different drug protocols.

Most of the 70 people relapsed when their treatment was interrupted, with the virus rebounding rapidly to pre-treatment levels. But 14 of them – four women and 10 men – were able to stay off of ARVs without relapsing, having taken the drugs for an average of three years.

The 14 adults still have traces of HIV in their blood, but at such low levels that their body can naturally keep it in check without drugs.

The 14 adults are not naturally resistant to HIV infection and are not currently taking any medication to control their HIV.

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