Month: February 2013 (page 12 of 13)

phthalates linked to obesity in black children

childhood obesity

Childhood obesity is a growing health concern in the United States. A new study has just come out showing that in black children, greater exposure to phthalates was linked to being overweight. From Scientific American:

Black children have much higher levels of the chemicals in their bodies than children of other races, and for every tripling of certain compounds, they were 22 percent more likely to be obese, according to data from 2,884 children aged 6 to 19. No links to obesity were found in white or Hispanic children.

“The takeaway is we need to consider environmental exposures when looking at the obesity problem,” said Leonardo Trasande, a professor at New York University School of Medicine and lead author of the study. “Environmental chemicals may contribute independently of diet and exercise.”

But of course correlation is not causation. And even if it were, no one can determine which problem might cause the other from this study:

It’s a big study and nationally representative, which is good,” said Joe Braun, an epidemiology professor at Brown University who was not involved with the research. “But since they measure phthalates levels in urine and obesity at the same time, it’s a chicken and egg problem. Do phthalates cause obesity or are obese children more exposed?” It’s unclear, he said, when they were exposed relative to when they became obese.

Much more here.

amoxicillin

amoxicillin

Amoxicillin

Over at SciAm, Lawrence Rifkin briefly discusses the history and benefits of amoxicillin:

Amoxicillin, a penicillin derivative, was synthesized by Beecham Research Laboratories in 1972. During cell wall synthesis, amoxicillin inhibits linear peptidoglycan polymer chains from being cross-linked, resulting in a defective bacterial cell wall and cell death. Compared to penicillin, amoxicillin offers a broader spectrum of bacteriocidal activity, greater duration, and, of course, better taste.

According to a report from the IMS Institute for Healthcare Informatics, in 2010 52.3 million prescriptions were written for amoxicillin in the U.S., more than any other antibiotic except azithromycin at 52.6 million. (The most prescribed drug in any category? Hydrocodone/acetaminophen, 131.2 million).

eat earlier. lose weight.

Lunch

Can eating earlier lunches help you lose weight? Maybe. A study of 420 adults in Boston and Spain seems to suggest so. From the abstract in the International Journal of Obesity:

Late lunch eaters lost less weight and displayed a slower weight-loss rate during the 20 weeks of treatment than early eaters (P=0.002). Surprisingly, energy intake, dietary composition, estimated energy expenditure, appetite hormones and sleep duration was similar between both groups. Nevertheless, late eaters were more evening types, had less energetic breakfasts and skipped breakfast more frequently that early eaters (all; P<0.05). CLOCK rs4580704 single nucleotide polymorphism (SNP) associated with the timing of the main meal (P=0.015) with a higher frequency of minor allele (C) carriers among the late eaters (P=0.041). Neither sleep duration, nor CLOCK SNPs or morning/evening chronotype was independently associated with weight loss (all; P>0.05).

Early eaters lost an average of 22lbs compared to 16.5lbs for later eaters.